| Effects of the menstrual cycle of white women on ethanol toxicokinetics.: An article from: Journal of Studies on Alcohol |  | Authors: Cristiana Leslie Correa, Seizi Oga
Publisher: Alcohol Research Documentation, Inc.
Category: Book
Buy New: $5.95
Format: Html
Media: Digital
Pages: 13
ASIN: B000829K7E
Publication Date: March 1, 2004
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Product Description
This digital document is an article from Journal of Studies on Alcohol, published by Alcohol Research Documentation, Inc. on March 1, 2004. The length of the article is 3871 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.
From the author: Objective: The aim of this study was to investigate the existing variations of the kinetics of ethanol in white women during the menstrual and luteal phases to further current understanding of the role of the menstrual cycle in gender differences in ethanol's adverse effects. Method: In a within-subjects design, 10 female white volunteers were administered a moderate dose of ethanol (0.3 g/kg) in the morning after an overnight fast. On each test day, blood samples were collected before ethanol administration so that hormonal (estrogen, progesterone, luteinizing hormone and follicle stimulating hormone) and biochemical (hepatic and renal functions) analyses could be performed. Blood samples were also drawn from each volunteer to determine BAC and to examine toxicokinetic differences between the two phases using classical and Widmark's measures. Results: The analysis of time-to-peak BAC in the two menstrual phases shows that there was no significant statistical difference when each phase was evaluated and in the interaction of the phase with time. The estimated toxicokinetic parameters did not show significant differences when the two phases were compared. Conclusions: Despite careful experimental design, which considered present debate and discussion in the literature, no significant differences between the two phases studied (menstrual and luteal) were observed. (J. Stud. Alcohol 65: 227-231, 2004)
Citation Details
Title: Effects of the menstrual cycle of white women on ethanol toxicokinetics.
Author: Cristiana Leslie Correa
Publication: Journal of Studies on Alcohol (Refereed)
Date: March 1, 2004
Publisher: Alcohol Research Documentation, Inc.
Volume: 65 Issue: 2 Page: 227(5)
Distributed by Thomson Gale
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